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Pustular Eruption in the ICU
Sometimes, appropriate treatment can introduce new problems for patients who are already seriously ill. This was true for a 62-year-old man with a history of chronic obstructive pulmonary disease,...
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Venous Gangrene
Venous Gangrene and Intravascular Coagulation and Fibrinolysis in a Patient Treated with Rivaroxaban Venous gangrene of the right lower extremity. Image taken on day of admission. A 67-year-old woman...
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Drug-induced Dilemma
Drug-induced Dilemma: Angiokeratomas and Decreased Renal Function Hemorrhagic papules were noted on the right thumb. Timing is everything, according to the well-worn aphorism. Yet, it certainly...
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It Took a Village: Good’s Syndrome
The patient presented with golf-ball-sized nodules on his extremities. A complex medical history became even more tangled when a 52-year-old man presented with a 4-week history of dry cough, dyspnea,...
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Increased Prevalence of Coronary Artery Disease in Severe Psoriasis and...
48-year-old man with severe psoriasis and calcified coronary lesions on CCTA (left); 57-year-old man with severe lifelong atopic dermatitis and mixed coronary plaque in the LAD on CCTA (middle), and no...
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Pyoderma Gangrenosum Associated with Acute Respiratory Distress Syndrome
Clinical manifestations of the left lower extremity, and X-ray and computed tomography images of the chest. (A) Painful deep ulcers with necrotic tissue and diffuse erosive purpura. (B) A butterfly...
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Treatment of Psoriasis with Mesenchymal Stem Cells
Clinical images. (A) Patient no. 1: (A1) Pre UC-MSCs infusions: well-defined erythematous plaques with adherent silvery scales symmetrically distributed throughout the body, mainly including the...
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Systemic Inflammation Gone Awry: PASH Syndrome and Temporomandibular Joint...
Left lower extremity with large ulcerations with hyperpigmented and indurated margins. The development of new symptoms in a patient with hidradenitis suppurativa led to the recognition of a systemic...
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Painful Violaceous Purpura on a 44-Year-Old Woman
A-C) Violaceous retiform purpura on the ear helix and lower extremities with associated histopathologic findings (hematoxylin-eosin, original magnification ×40). Returning to the fundamentals of our...
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A Diagnosis at Hand: Pulmonary Arterial Hypertension
A classic physical examination finding pointed to underlying disease in a 43-year-old Hispanic woman. On presenting to the Emergency Department, she reported progressive shortness of breath, fatigue,...
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Ongoing Pleuritic Chest Pain and a Guinea Pig: Missed Pulmonary Embolism and...
Oval erythematous patch with approximately 10 to 20 2- to 3-mm erythematous pustules located on the right lower abdomen. A 27-year-old woman presented for a second opinion with chest pain, dyspnea,...
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Scabies Outbreak in the 14th Century: Clues from Correspondence Between Poets
The deleterious effects of scabies, an infestation of the skin by the human itch mite Sarcoptes scabiei var. hominis, were well known in the Middle Ages. Here we report descriptions of medieval...
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Skin Lesion with Splenic Microabscesses in a Patient with Acute Myeloid Leukemia
A 42-year-old male patient with acute myeloid leukemia was admitted to the hospital to start induction chemotherapy with idarubicin, cytarabine, and cytarabine. He was started on levofloxacin and...
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Silver-Containing Wound Cream Leading to Argyria—Always Ask About Alternative...
Azure lunula, blue discoloration of nails. Currently, patients are increasingly gaining access to medications and nutritional supplements via the Internet from companies that are not subject to any...
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Primary Care Management of Skin Abscesses Guided by Ultrasound
(A) Patient abscess with internal loculations (arrow). (B) Patient abscess with tracking (arrows). Primary care providers often manage skin abscesses in the outpatient setting. Estimating the size and...
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Doubly Dangerous: Extranodal NK/T-Cell Lymphoma
The clinical manifestations of the disease were evident. (A) The patient had symmetrical violaceous swelling on both cheeks. Deep-seated induration occurred on palpation. (B) Faint violaceous patches...
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Transverse Lines of the Nails
Transverse lines of the fingernails. (A) Beau’s lines (arrows) of the thumbnail. (B) Mees’ lines (arrowheads) of the thumbnail. Four distinct, transverse, depressed lines (Figure, A) developed on the...
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Not Just Skin Deep: Distant Metastases from Cutaneous Squamous Cell Carcinoma
Portable chest x-ray on presentation (A) and follow-up computed tomography of the chest without contrast (B). Cutaneous squamous cell carcinoma is the second most common cancer in the United States...
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Four Cancers and a Rash: Henoch–Schönlein Purpura
The patient had dorsal edema and purpura on both hands. A patient who had a history of 4 primary malignancies developed a rash that is usually seen among children. The 65-year-old man presented with a...
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Disseminated Zoster After Trauma in an Immunocompetent Patient
Photograph of the patient’s multi-dermatomal vesicular rash. Lesions are shown on the right face, neck, and chest. An 88-year-old man presented to the emergency department with dizziness and...
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